Family Foundation Model

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Aminoacyltransferase

A protein family as ChEMBL classifies it.

Targets

6

servable in this model

Ligands

198

measured here and in at least one other family

Comparisons

237

involving this family

The data

QuantityValue
Measurements237
Activity range, pActivity3.0 to 8.62
Median activity5.64

Endpoints

EndpointMeasurements
IC50214
Ki23

Comparing two targets inside this family

This family carries 15 held-out comparisons between two of its own targets, below the 200 this site requires before publishing an accuracy, so none is published for it. The tool still answers, and labels the answer with the figure measured across every family, 0.78 on 32,738 comparisons.

355 comparisons between two targets in this family were formed from 158 compounds over 5 proteins, and entered the fit or the holdout.

How far its compounds reach

Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.

Families a compound reachesCompounds
Two191
Three2
Four or more5

Which families those compounds also reach

FamilyShared compounds
Transferase101
Kinase91
Protease6
Oxidoreductase5
Cytochrome P4504
Hydrolase3

Targets in this family

Accession
O95932
P00488
P21980
P22735
Q08188
Q16769