Enzymes that catalyze electron transfer, including the cyclooxygenases.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 10,199 |
| Activity range, pActivity | 0.7 to 10.71 |
| Median activity | 5.52 |
| Endpoint | Measurements |
|---|---|
| IC50 | 8,445 |
| Kd | 873 |
| Ki | 821 |
| EC50 | 60 |
| Quantity | Value |
|---|---|
| Held-out comparisons inside this family | 1,137 |
| Accuracy on them | 0.79 |
| Distinct proteins behind that figure | 86 |
Read the accuracy with the protein count beside it: it describes those 86 proteins as much as it describes the family. A family prior says nothing here, because both targets carry the same label, so every point above 0.50 comes from the comparison itself.
11,349 comparisons between two targets in this family were formed from 8,075 compounds over 156 proteins, and entered the fit or the holdout.
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 2,610 |
| Three | 316 |
| Four or more | 275 |