Enzymes that cleave peptide bonds.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 6,624 |
| Activity range, pActivity | 1.28 to 11.17 |
| Median activity | 5.81 |
| Endpoint | Measurements |
|---|---|
| IC50 | 5,733 |
| Ki | 811 |
| Kd | 69 |
| EC50 | 11 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 2,269 |
| Three | 157 |
| Four or more | 135 |
| Family | Shared compounds |
|---|---|
| Hydrolase | 777 |
| Cytochrome P450 | 560 |
| Voltage-gated ion channel | 469 |
| Oxidoreductase | 323 |
| Kinase | 228 |
| Lyase | 141 |