Epigenetic proteins that remove a histone mark.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 6,808 |
| Activity range, pActivity | 0.42 to 11.16 |
| Median activity | 6.37 |
| Endpoint | Measurements |
|---|---|
| IC50 | 6,439 |
| Ki | 265 |
| Kd | 64 |
| EC50 | 40 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 1,665 |
| Three | 125 |
| Four or more | 103 |
| Family | Shared compounds |
|---|---|
| Oxidoreductase | 645 |
| Kinase | 498 |
| Transferase | 246 |
| Voltage-gated ion channel | 146 |
| Protease | 124 |
| Cytochrome P450 | 100 |