Channels that open when a ligand binds, rather than on voltage.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 2,008 |
| Activity range, pActivity | 2.56 to 10.4 |
| Median activity | 5.98 |
| Endpoint | Measurements |
|---|---|
| Ki | 1,163 |
| IC50 | 675 |
| EC50 | 169 |
| Kd | 1 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 436 |
| Three | 55 |
| Four or more | 65 |
| Family | Shared compounds |
|---|---|
| Family A G protein-coupled receptor | 298 |
| Cytochrome P450 | 138 |
| Voltage-gated ion channel | 120 |
| Electrochemical transporter | 69 |
| Protease | 32 |
| Hydrolase | 32 |