A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 1,389 |
| Activity range, pActivity | 1.18 to 10.19 |
| Median activity | 5.26 |
| Endpoint | Measurements |
|---|---|
| IC50 | 1,312 |
| Ki | 54 |
| Kd | 23 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 335 |
| Three | 45 |
| Four or more | 68 |
| Family | Shared compounds |
|---|---|
| Oxidoreductase | 101 |
| Hydrolase | 100 |
| Protease | 97 |
| Voltage-gated ion channel | 83 |
| Kinase | 64 |
| Transferase | 51 |