Enzymes that break bonds by means other than hydrolysis or oxidation.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 2,922 |
| Activity range, pActivity | 0.54 to 10.34 |
| Median activity | 5.54 |
| Endpoint | Measurements |
|---|---|
| Ki | 1,586 |
| IC50 | 700 |
| Kd | 603 |
| EC50 | 33 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 329 |
| Three | 40 |
| Four or more | 71 |
| Family | Shared compounds |
|---|---|
| Protease | 141 |
| Hydrolase | 114 |
| Kinase | 96 |
| Family A G protein-coupled receptor | 92 |
| Oxidoreductase | 86 |
| Transferase | 51 |