Epigenetic proteins that recognize a histone mark.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 2,043 |
| Activity range, pActivity | 3.08 to 9.4 |
| Median activity | 6.43 |
| Endpoint | Measurements |
|---|---|
| IC50 | 1,766 |
| Kd | 253 |
| Ki | 24 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 597 |
| Three | 40 |
| Four or more | 30 |
| Family | Shared compounds |
|---|---|
| Kinase | 449 |
| Eraser | 89 |
| Transferase | 65 |
| Voltage-gated ion channel | 37 |
| Cytochrome P450 | 36 |
| Writer | 31 |