Enzymes that rearrange a molecule into an isomer.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 1,132 |
| Activity range, pActivity | 3.39 to 9.7 |
| Median activity | 5.72 |
| Endpoint | Measurements |
|---|---|
| IC50 | 869 |
| Kd | 145 |
| Ki | 112 |
| EC50 | 6 |
This family carries 39 held-out comparisons between two of its own targets, below the 200 this site requires before publishing an accuracy, so none is published for it. The tool still answers, and labels the answer with the figure measured across every family, 0.78 on 32,738 comparisons.
448 comparisons between two targets in this family were formed from 319 compounds over 26 proteins, and entered the fit or the holdout.
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 366 |
| Three | 43 |
| Four or more | 56 |
| Family | Shared compounds |
|---|---|
| Oxidoreductase | 328 |
| Cytochrome P450 | 47 |
| Phosphatase | 43 |
| Kinase | 42 |
| Primary active transporter | 36 |
| Electrochemical transporter | 32 |