Ligand-activated transcription factors.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 3,265 |
| Activity range, pActivity | -0.54 to 10.99 |
| Median activity | 6.49 |
| Endpoint | Measurements |
|---|---|
| IC50 | 2,408 |
| Ki | 515 |
| EC50 | 318 |
| Kd | 24 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 859 |
| Three | 97 |
| Four or more | 139 |
| Family | Shared compounds |
|---|---|
| Cytochrome P450 | 370 |
| Voltage-gated ion channel | 300 |
| Family A G protein-coupled receptor | 237 |
| Oxidoreductase | 149 |
| Kinase | 133 |
| Eraser | 86 |